钙粘蛋白29抗体
规格:1尘驳/1尘濒
英文名: CDH29
别名: Cadherin-like protein 29; Cadherin-related family member 4; CDH29; CDHR4; CDHR4_HUMAN; UNQ9392/PRO34300; VLLR9392.
分子量: 86kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CDH29
交叉反应:Human, Mouse, Pig, Horse,
细胞定位:细胞膜
钙粘蛋白29抗体产物介绍:background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-29, also known as Cadherin-related family member 4, is a 788 amino acid single-pass type I membrane protein that has four cadherin domains. There are two isoforms of cadherin-29 that are produced as a result of alternative splicing events. The gene encoding cadherin-29 钙粘蛋白29抗体maps to human chromosome 3, which is is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in 钙粘蛋白29抗体a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Membrane. Tissue Specificity: Contains 4 cadherin domains. Similarity: Contains 4 cadherin domains. Gene ID: 389118 Database links: Entrez Gene: 389118 Human SwissProt: A6H8M9 Human Unigene: 363312 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙粘蛋白29抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid