几丁质酶1抗体
规格：1尘驳/1尘濒
英文名： CHIT1
别名： CHI3; CHIT; CHIT1; CHIT1_HUMAN; CHITD; Chitinase 1; Chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHIT1
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：细胞浆
几丁质酶1抗体产物介绍：background: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly几丁质酶1抗体 regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012] Function: Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. Subcellular Location: Secreted. Lysosome几丁质酶1抗体. A small proportion is lysosomal. Tissue Specificity: Detected in spleen. Secreted by cultured macrophages. Similarity: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. Contains 1 chitin-binding type-2 domain. Gene ID: 1118 Database links: Entrez Gene: 1118 Human Omim: 600031 Human SwissProt: Q13231 Human Unigene: 201688 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
几丁质酶1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid