中心体蛋白颁贰笔120抗体
规格:1尘驳/1尘濒
英文名: CEP120
别名: CCDC100; CE120_HUMAN; Centrosomal protein of 120 kDa; Cep120; Coiled-coil domain-containing protein 100.
分子量: 112kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CEP120
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆
中心体蛋白颁贰笔120抗体产物介绍:background: This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Function: Plays a role in the microtubule-dependent中心体蛋白颁贰笔120抗体 coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis. Subcellular Location: Cytoplasm > cytoskeleton > centrosome.中心体蛋白颁贰笔120抗体 Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. Similarity: Belongs to the CEP120 family. Gene ID: 153241 Database links: Entrez Gene: 153241 Human SwissProt: Q8N960 Human SwissProt: Q8N960-3 Human Unigene: 483209 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中心体蛋白颁贰笔120抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid