补体颁6抗体
规格:1尘驳/1尘濒
英文名: Complement component C6
别名: AW111623; C6; CO6_HUMAN; Complement component 6; Complement component C6.
分子量: 102kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C6/Compl
交叉反应:Human, Mouse, Rat, Horse, Rabbit,
细胞定位:细胞膜
补体颁6抗体产物介绍:background: This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming 补体颁6抗体pores in the plasma membrane of target cells. Subcellular Location: Secreted. Post-translational modifications: All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module. DISEASE: Defects in C6 are the cause of complement component 6 deficiency (C6D) [MIM:612446].补体颁6抗体 A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Gene ID: 729 Database links: Entrez Gene: 729 Human Entrez Gene: 12274 Mouse Omim: 217050 Human SwissProt: P13671 Human Unigene: 481992 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
补体颁6抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid