5-羟色胺受体5叠抗体
规格：1尘驳/1尘濒
英文名： 5HT5B Receptor
别名： 5 HT 5B; 5 HT5B; 5 hydroxytryptamine receptor 5B; 5ht5b; Htr5b; REC17; Serotonin receptor 5B; 5HT5B_MOUSE.
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse 5HT5B Re
交叉反应：Mouse, Rat, Rabbit,
细胞定位：细胞膜
5-羟色胺受体5叠抗体产物介绍：background: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and entero-chromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions 5-羟色胺受体5叠抗体of the nucleus. Serotonin receptors include SR-1–7 (5-HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, 5-羟色胺受体5叠抗体and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed predominantly in the central nervous system; in the hippocampus, habenula, and the doral raphe. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 15564 Database links: Entrez Gene: 15564 Mouse Entrez Gene: 79247 Rat SwissProt: P31387 Mouse SwissProt: P35365 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-羟色胺受体5叠抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid