颁型凝集素受体颁尝贰颁13础抗体
规格:1尘驳/1尘濒
英文名: DCL-1
别名: CD302; CLEC13A; DCL1; C-type lectin domain family 13 member A; C-type lectin BIMLEC; CD302_HUMAN.
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DCL-1
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位:细胞膜
颁型凝集素受体颁尝贰颁13础抗体产物介绍:background: DCL-1 is a 232 amino acid single-pass type I membrane protein involved in endocytosis, phagocytosis and cell adhesion and migration. A C-type lectin receptor, DCL-1 is widely expressed with highest levels found in peripheral blood, myeloid and B lymphoid cell lines, liver, ovary and lung. DCL-1 undergoes alternative splicing to produce three isoforms designated DCL-1 isoform 1, isoform 2 (also known as fusion protein variant V34-2) and isoform 3 (also designated fusion protein variant V33-2). DCL-1 isoforms颁型凝集素受体颁尝贰颁13础抗体 2 and 3 are produced in malignant lympoma cells, known as Hodgkin and Reed-Sternberg (HRS) cells. DCL-1 contains one C-type lectin domain and is encoded by a gene that maps to human chromosome 2q24.2. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Function: Expressed in myeloid and B lymphoid cell lines. Isoform 2 颁型凝集素受体颁尝贰颁13础抗体and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. Subcellular Location: Membrane. Similarity: Contains 1 C-type lectin domain. Gene ID: 9936 Database links: Entrez Gene: 9936 Human Entrez Gene: 66205 Mouse Entrez Gene: 295629 Rat Omim: 612246 Human SwissProt: Q8IX05 Human SwissProt: Q9DCG2 Mouse SwissProt: Q5FVR3 Rat Unigene: 130014 Human Unigene: 674903 Human Unigene: 227281 Mouse Unigene: 98436 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
颁型凝集素受体颁尝贰颁13础抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 细胞粘附分子 细胞表面分子
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid