紧密连接蛋白23抗体
规格：1尘驳/1尘濒
英文名： Claudin 23
别名： 2310014B08Rik; Claudin23; CLDN 23; CLDN23; CLDNL; CLD23_HUMAN.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Claudin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞膜
紧密连接蛋白23抗体产物介绍：background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center紧密连接蛋白23抗体 B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80% sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor紧密连接蛋白23抗体. Subcellular Location: Integral membrane protein. Tight junctions Similarity: Belongs to the claudin family. Gene ID: 137075 Database links: Entrez Gene: 137075 Human Entrez Gene: 71908 Mouse Omim: 609203 Human SwissProt: Q96B33 Human SwissProt: Q9D7D7 Mouse Unigene: 183617 Human Unigene: 37817 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
紧密连接蛋白23抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid