笔搁贰尝笔蛋白抗体
规格：1尘驳/1尘濒
英文名： PRELP
别名： 55 kDa leucine rich repeat protein of articular cartilage; MST161; MSTP161; Prelp; PRELP_HUMAN; Prolargin; Prolargin proteoglycan; Proline arginine rich end leucine rich repeat protein; Proline-argini
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PRELP
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位：细胞浆
笔搁贰尝笔蛋白抗体产物介绍：background: PRELP (proline/arginine-rich end leucine-rich repeat protein), also known as Prolargin, MST161, SLRR2A or MSTP161, is a 382 amino acid secreted protein that localizes to the extracellular matrix. Belonging to the Class II subfamily of the small leucine-rich proteoglycan (SLRP) family, PRELP contains twelve LRR (leucine-rich) repeats, which are motifs consisting of 20-29 residues that are present in numerous proteins with diverse functions and provide versatile structural framework for the formation of protein-protein interactions. Highly expressed in cartilage, basement membranes and developing bone, PRELP is considered a glycosaminoglycan (GAG)- and笔搁贰尝笔蛋白抗体 collagen-binding anchor protein that associates with the basement membrane heparan sulfate proteoglycan perlecan. PRELP acts as a linker between the extracellular matrix and the cell surface of proteoglycans and may be partially responsible for Hutchinson-Gilford progeria (HGP), an extremely rare genetic disorder that causes premature, rapid aging shortly after birth. Function: May anchor basement membranes to 笔搁贰尝笔蛋白抗体the underlying connective tissue. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Connective tissue. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. Contains 12 LRR (leucine-rich) repeats. Gene ID: 5549 Database links: Entrez Gene: 5549 Human Omim: 601914 Human SwissProt: P51888 Human Unigene: 632481 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
笔搁贰尝笔蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid