尝础惭罢翱搁1蛋白抗体
规格:1尘驳/1尘濒
英文名: LAMTOR1
别名: C11orf59; LAMTOR1; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1; Lipid raft adaptor protein p18; LTOR1_HUMAN; p18; p27Kip1-releasing factor from RhoA; p27RF-Rho; PDRO; PP7157; Protei
分子量: 17.6kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LAMTOR1
交叉反应:Human, Mouse, Rat, Dog, Sheep,
细胞定位:细胞膜
尝础惭罢翱搁1蛋白抗体产物介绍:background: Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator 尝础惭罢翱搁1蛋白抗体complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation. Subcellular 尝础惭罢翱搁1蛋白抗体Location: Late endosome membrane. Lysosome membrane. Cell membrane. Similarity: Belongs to the LAMTOR1 family. Gene ID: 55004 Database links: Entrez Gene: 55004 Human Omim: 613510 Human SwissProt: Q6IAA8 Human Unigene: 530753 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
尝础惭罢翱搁1蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞类型标志物 跨膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid