睾丸特异性蛋白57抗体
规格：1尘驳/1尘濒
英文名： CEP57
别名： Centrosomal protein 57kDa; Centrosomal protein of 57 kDa; Cep57; Cep57 protein; CEP57_HUMAN; FGF2 interacting protein; FGF2-interacting protein; KIAA0092; MVA2; PIG8; Proliferation inducing protein 8;
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CEP57
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：细胞核 细胞浆
睾丸特异性蛋白57抗体产物介绍：background: CEP57 (centrosomal protein 57kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis,睾丸特异性蛋白57抗体 possibly via the indirect regulation of gene expression. Human CEP57 shares 88% sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events. Function: Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2. Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity睾丸特异性蛋白57抗体 Ubiquitous. Similarity: Belongs to the translokin family. Gene ID: 9702 Database links: Entrez Gene: 9702 Human Entrez Gene: 353245 Cow Entrez Gene: 74360 Mouse Entrez Gene: 315423 Rat Omim: 607951 Human SwissProt: Q865V0 Cow SwissProt: Q86XR8 Human SwissProt: Q8CEE0 Mouse SwissProt: B4F7A7 Rat Unigene: 101014 Human Unigene: 157212 Mouse Unigene: 94972 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
睾丸特异性蛋白57抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 干细胞 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid