锌指蛋白903抗体
规格：1尘驳/1尘濒
英文名： ZBTB4
别名： KAISO-L1; KAISO-like zinc finger protein 1; KIAA1538; ZBTB4; ZBTB4_HUMAN; Zinc finger and BTB domain containing 4; Zinc finger and BTB domain-containing protein 4; ZNF903.
分子量： 105kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZBTB4/ZN
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
锌指蛋白903抗体产物介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZBTB4 (zinc finger and BTB domain containing 4), also known as KAISO-L1 (KAISO-like zinc finger protein 1), is a 1,013 amino acid nuclear protein that is involved in transcriptional regulation. ZBTB4 contains one BTB (POZ) domain, six C2H2-type zinc fingers and is phosphorylated and downregulated by HIPK2. The锌指蛋白903抗体 gene encoding ZBTB4 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Function: May be involved in transcriptional regulation. Subunit: Interacts with HIPK2. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated by HIPK2. This phosphorylation reduces stability and triggers ZBTB4 protein degradation in response to锌指蛋白903抗体 DNA damage. Similarity: Contains 1 BTB (POZ) domain. Contains 6 C2H2-type zinc fingers. Database links: Entrez Gene: 57659 Human Entrez Gene: 75580 Mouse Entrez Gene: 287441 Rat Omim: 612308 Human SwissProt: Q9P1Z0 Human Unigene: 35096 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白903抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid