骋蛋白偶联受体100抗体
规格:1尘驳/1尘濒
英文名: GPR100
别名: G protein coupled receptor 100; G-protein coupled receptor 100; G-protein coupled receptor GPCR142; GPCR142; Insulin-like peptide INSL5 receptor; Relaxin 3 receptor 2; Relaxin family peptide receptor
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human G protei
交叉反应:Human, Mouse, Pig, Cow, Rabbit,
细胞定位:细胞膜
骋蛋白偶联受体100抗体产物介绍:background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. Relaxin Receptor 4, also known as Relaxin/insulin-like family骋蛋白偶联受体100抗体 peptide receptor 4, RXFP4, RLN3R2, GPCR142 or GPR100, is a G protein-coupled receptor that binds Relaxin 3 and is specifically expressed in peripheral tissues, particularly in the colon. Function: High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in a骋蛋白偶联受体100抗体 broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 339403 Database links: Entrez Gene: 339403 Human Entrez Gene: 242093 Mouse Omim: 609043 Human SwissProt: Q8TDU9 Human SwissProt: Q7TQP4 Mouse Unigene: 449914 Human Unigene: 269130 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体100抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid