死亡相关蛋白5抗体
规格:1尘驳/1尘濒
英文名: DAP5
别名: DAP-5; DAP 5; Death Associated Protein-5; Death associated protein 5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; Nat1; No
分子量: 102kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DAP-5
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
细胞定位:细胞浆
死亡相关蛋白5抗体产物介绍:background: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible死亡相关蛋白5抗体 for the mediation of its own translation during apoptosis. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous. Gene ID: 1982 Database links: Entrez Gene: 1982 Human Entrez Gene: 13690 Mouse Entrez Gene: 361628 Rat Omim: 602325 Human SwissProt:死亡相关蛋白5抗体 P78344 Human SwissProt: Q62448 Mouse Unigene: 183684 Human Unigene: 185453 Mouse Unigene: 103276 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. DAP-5又称p97, 是白细胞转移抑制因子4G (ELF4G)家族成员. DAP-5在各种种系表达广泛并高度保守。
死亡相关蛋白5抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid