贵补蝉相关1因子抗体
规格:1尘驳/1尘濒
英文名: FAF1
别名: Fas associated factor 1; CGI; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1
分子量: 74kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FAF1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,
细胞定位:细胞核
贵补蝉相关1因子抗体产物介绍:background: FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; 贵补蝉相关1因子抗体HFAF1s; Protein FAF1; TNFRSF6 associated factor 1. Function: Potentiates but cannot initiate FAS-induced apoptosis. Subunit: Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain. Subcellular Location: Nucleus. Tissue Specificity: Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary,贵补蝉相关1因子抗体 small intestine, and colon. Not detected in the peripheral blood leukocytes. Similarity: Contains 1 UBA domain. Contains 1 UBX domain. Gene ID: 11124 Database links: Entrez Gene: 11124 Human Entrez Gene: 14084 Mouse Entrez Gene: 140657 Rat Omim: 604460 Human SwissProt: Q9UNN5 Human SwissProt: P54731 Mouse SwissProt: Q924K2 Rat Unigene: 530402 Human Unigene: 318259 Mouse Unigene: 198288 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵补蝉相关1因子抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid