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高尔基体膜相关蛋白7抗体

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产物名称: 高尔基体膜相关蛋白7抗体
产物型号: GOLGA7
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

高尔基体膜相关蛋白7抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。高尔基体膜相关蛋白7抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


高尔基体膜相关蛋白7抗体  的详细介绍

高尔基体膜相关蛋白7抗体

规格:1尘驳/1尘濒

英文名: GOLGA7

别名: GCP 16; GCP16; GOLGA 7; GOLGA3AP1; GOLGA7A; Golgi autoantigen golgin subfamily a 7; Golgi complex associated protein of 16kDa; Golgin A7; Golgin subfamily A member 7; HSPC041; MGC21096; MGC4876; GOGA7

分子量: 16kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human GOLGA7

交叉反应:Human, Mouse, Rat, Sheep,

细胞定位:细胞浆 细胞膜

高尔基体膜相关蛋白7抗体产物介绍:background: GOLGA7 is a multi-pass membrane protein belonging to the Erf4 family of proteins. It is the functional ortholog of the yeast Erf4 protein. Localizing to the Golgi apparatus, GOLGA7 is a widely expressed protein but its expression is absent from colon and thymus tissues. GOLGA7 is palmitoylated on two cysteine residues, and this palmitoylation is required for its interaction with golgin 160 and its Golgi-localization. GOLGA7 also forms a complex with ZDHHC9 and, together, these proteins function as a Ras palmitoyltransferase (Ras PAT) which is required for palmitoylation of H-Ras and N-Ras proteins. The palmitoylation of Ras proteins is essential for the trafficking高尔基体膜相关蛋白7抗体 of Ras proteins from the Golgi to the plasma membrane, thus implicating GOLGA7 in protein transport from the Golgi to the cell surface. Function: GOLGA7 (Golgi autoantigen, golgin subfamily a, 7) is a member of the golgin family and may be involved in protein transport from the Golgi to the cell surface. GOLGA7 forms a protein complex with ZDHHC9. This ZDHHC9-GOLGA7 complex is a palmitoyltransferase高尔基体膜相关蛋白7抗体 specific for H-RAS and N-RAS. Subunit: Interacts with GOLGA3. Interacts with ZDHHC9. Subcellular Location: Golgi apparatus membrane; Lipid-anchor Tissue Specificity: Expressed in all tissues except colon and thymus. Post-translational modifications: Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3. Similarity: Belongs to the ERF4 family. Database links: UniProtKB/Swiss-Prot: Q7Z5G4.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

高尔基体膜相关蛋白7抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  细胞类型标志物  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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