高尔基体膜相关蛋白抗体
规格:1尘驳/1尘濒
英文名: GOLGA3
别名: GCP170; GOLGA 3; GOLGA3; Golgi autoantigen; Golgi complex associated protein of 170 kDa; Golgi complex-associated protein of 170 kD; Golgi membrane associated protein; Golgi peripheral membrane protei
分子量: 167kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GOLGA3/G
交叉反应:Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位:细胞浆
高尔基体膜相关蛋白抗体产物介绍:background: The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts 高尔基体膜相关蛋白抗体with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events. Function: GOLGA3 is a member of the golgin family of proteins which are localized to the Golgi. It has been postulated to play a role in nuclear transport and Golgi apparatus localization. Subunit: Homodimerv. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not. Subcellular Location: Cytoplasmic and Golgi Apparatus. Tissue Specificity: Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney. Post-translational modifications: Cleaved by caspases in apoptotic cells. Database links: Entrez Gene: 2802 Human Omim: 602581 Human SwissProt: Q08378 Human Unigene: 507333 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
高尔基体膜相关蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid