甘露糖脱水酶骋惭顿厂抗体
规格:1尘驳/1尘濒
英文名: GMDS
别名: GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; Gmds; GMDS_HUMAN; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehyd
分子量: 42kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GMDS
交叉反应:Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Zebrafish,
细胞定位:
甘露糖脱水酶骋惭顿厂抗体产物介绍:background: GMD is a 372 amino acid protein that utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. GMD mutations are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. The gene encoding GMD maps to human chromosome 6, which contains 170 million 甘露糖脱水酶骋惭顿厂抗体base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function:甘露糖脱水酶骋惭顿厂抗体 Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose. Similarity: Belongs to the GDP-mannose 4,6-dehydratase family. Database links: UniProtKB/Swiss-Prot: O60547.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甘露糖脱水酶骋惭顿厂抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 转运蛋白 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid