核呼吸因子-1抗体
规格：1尘驳/1尘濒
英文名： NRF1/TCF11
别名： erythroid derived 2; like 1; Locus control region factor 1; Locus control region-factor 1; NF-E2-related factor 1; NF2L1_HUMAN; NFE2 related factor 1; NFE2-related factor 1; NFE2L1; NRF1; NRF-1; NRF 1
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NRF1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 线粒体
核呼吸因子-1抗体产物介绍：background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms核呼吸因子-1抗体 have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1. [provided by RefSeq]核呼吸因子-1抗体. Function: Activates erythroid-specific, globin gene expression. Subunit: Interacts with KEAP1. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus. Similarity: Belongs to the bZIP family. CNC subfamily. Contains 1 bZIP (basic-leucine zipper) domain. Gene ID: 4899 Database links: Entrez Gene: 4899 Human Omim: 600879 Human SwissProt: Q16656 Human Unigene: 654363 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NRF-1是核基因编码且影响mtDNA的另一重要因子, 他控制着线粒体电子传递链的一些蛋白质的合成。
核呼吸因子-1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：染色质和核信号 转录调节因子 合成与降解 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid