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谷氧还蛋白5抗体

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产物名称: 谷氧还蛋白5抗体
产物型号: Glutaredoxin 5
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

谷氧还蛋白5抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。谷氧还蛋白5抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


谷氧还蛋白5抗体  的详细介绍

谷氧还蛋白5抗体

规格:1尘驳/1尘濒


英文名: Glutaredoxin 5

别名: C14orf87; Chromosome 14 open reading frame 87; FLB4739; GLRX 5; Glrx5; GLRX5_HUMAN; Glutaredoxin 5 homolog; Glutaredoxin related protein 5; Glutaredoxin-related protein 5; Glutaredoxin5; GRX5; MGC1412

分子量: 14kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human Glutared

交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,

细胞定位:细胞浆 线粒体

谷氧还蛋白5抗体产物介绍:background: This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010] Function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. Subunit: Homodimer. Subcellular Location: Mitochondrion. DISEASE: Defects in GLRX5 are a cause of anemia sideroblastic pyridoxine-refractory谷氧还蛋白5抗体 autosomal recessive (PRARSA) [MIM:205950]. A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. Similarity: Belongs to the glutaredoxin family. Monothiol subfamily. Contains 1 glutaredoxin domain. Gene ID: 51218 Database links: Entrez Gene: 谷氧还蛋白5抗体51218 Human Entrez Gene: 73046 Mouse Entrez Gene: 362776 Rat Omim: 609588 Human SwissProt: Q86SX6 Human SwissProt: Q80Y14 Mouse Unigene: 532683 Human Unigene: 728210 Human Unigene: 29128 Mouse Unigene: 104008 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

谷氧还蛋白5抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  细胞生物  信号转导  新陈代谢  线粒体  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid



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