糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体
规格:1尘驳/1尘濒
英文名: GLT25D1
别名: FLJ22329; Glycosyltransferase 25 domain containing 1; Hydroxylysine galactosyltransferase 1; Procollagen galactosyltransferase 1; GT251_HUMAN.
分子量: 69kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GLT25D1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体产物介绍:background: GLT25D1 is a 622 amino acid protein that localizes to the lumen of the endoplasmic reticulum. Ubiquitously expressed with higher levels in placenta, heart, lung and spleen, GLT25D1 is a member of the glycosyltransferase 25 family. The beta-galactosyltransferase activity of GLT25D1 allows the transfer of beta-galactose to hydroxylysine residues of collagen. GLT25D1 is considered an important target for investigating the biological significance of collagen glycosylation糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体 and the importance of posttranslational modification in the etiology of connective tissue disorders. The gene encoding GLT25D1 is located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Function: Has a beta-galactosyltransferase activity; 糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体transfers beta-galactose to hydroxylysine residues of collagen. Subcellular Location: Endoplasmic reticulum lumen. Note: Colocalized with PLOD3 and mannose binding lectin. Tissue Specificity: Ubiquitous with higher levels in placenta, heart, lung and spleen. Post-translational modifications: N-glycosylated. Similarity: Belongs to the glycosyltransferase 25 family. Database links: UniProtKB/Swiss-Prot: Q8NBJ5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 新陈代谢 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid