顿狈础修复蛋白骋滨驰顿2抗体
规格：1尘驳/1尘濒
英文名： GIYD2
别名： FLJ23439; GIY YIG domain containing 2; GIYD 2; MGC2532; MGC5178； SLX1_HUMAN.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GIYD2
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：
顿狈础修复蛋白骋滨驰顿2抗体产物介绍：background: This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through顿狈础修复蛋白骋滨驰顿2抗体 transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. Function: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex顿狈础修复蛋白骋滨驰顿2抗体 DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. Subunit: Forms a heterodimer with SLX4. Subcellular Location: Nucleus. Similarity: Belongs to the SLX1 family. Contains 1 GIY-YIG domain. Contains 1 SLX1-type zinc finger. Database links: UniProtKB/Swiss-Prot: Q9BQ83.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿狈础修复蛋白骋滨驰顿2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid