脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体
规格:1尘驳/1尘濒
英文名: MBOAT4
别名: FKSG89; ghrelin o transferas; Ghrelin O-acyltransferase; GOAT; MBOA4_HUMAN; Mboat4; Membrane-bound O-acyltransferase domain-containing protein 4; O-acyltransferase (membrane bound) domain containing 4
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Ghrelin
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit, Monkey, Gorilla
细胞定位:细胞浆 细胞膜
脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体产物介绍:background: MBOAT4 (membrane-bound O-acyltransferase domain-containing protein 4, Ghrelin O-acyltransferase) is a 435 amino acid, multi-pass membrane protein that belongs to the membrane-bound acyltransferase family. MBOAT4 functions as an enzyme that attaches an octanoate fatty acid to serine-3 of ghrelin. Ghrelin is a very small, appetite-stimulating hormone secreted by the food-deprived stomach. MBOAT4 can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. MBOAT4 expression, consistent with its function, is mainly in the stomach and intestines. Due to its 脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体primary function, MBOAT4 is a candidate for obesity and appetite suppression studies. Function: Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity:脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体 Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues. Similarity: Belongs to the membrane-bound acyltransferase family. Database links: Entrez Gene: 619373 Human Entrez Gene: 234155 Mouse Omim: 611940 Human SwissProt: Q96T53 Human SwissProt: P0C7A3 Mouse Unigene: 627194 Human Unigene: 324008 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid