顿-果糖6磷酸转移酶2抗体
规格：1尘驳/1尘濒
英文名： GFPT2
别名： D fructose 6 phosphate amidotransferase 2; GFAT 2; GFAT2; Glucosamine fructose 6 phosphate aminotransferase [isomerizing] 2; glutamine fructose 6 phosphate transaminase 2; Glutamine:fructose 6 phospha
分子量： 77kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GFPT2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
顿-果糖6磷酸转移酶2抗体产物介绍：background: GFPT2 (glutamine-fructose-6-phosphate transaminase 2), also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis. Expressed in spinal cord, heart and placenta, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for 顿-果糖6磷酸转移酶2抗体N- and O-linked protein glycosylation. Containing one glutamine amidotransferase type-2 domain and two SIS domains. GFAT2 is encoded by a gene that maps to human chromosome 5q35.3. GFAT2 gene variants have been linked to type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. Function: GFPT2, also known as glutamine fructose 6 phosphate transaminase 2, controls the flux of glucose into the hexosamine pathway. It is probably involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Tissue Specificity:顿-果糖6磷酸转移酶2抗体 Highest levels of expression in heart, placenta, and spinal cord. Similarity: Contains 1 glutamine amidotransferase type-2 domain. Contains 2 SIS domains. Database links: UniProtKB/Swiss-Prot: O94808.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿-果糖6磷酸转移酶2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid