广泛控制氨基酸合成1样蛋白1抗体
规格:1尘驳/1尘濒
英文名: Gcn1l1
别名: GCN1; GCN1 (general control of amino acid synthesis yeast homolog) like; GCN1 (general control of amino acid synthesis 1 yeast) like 1; GCN1 general control of amino acid synthesis 1 like 1; GCN1 gene
分子量: 293kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Gcn1l1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:细胞浆
广泛控制氨基酸合成1样蛋白1抗体产物介绍:background: GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over广泛控制氨基酸合成1样蛋白1抗体 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. Function: Gcn1l1 acts as a translation activator which mediates translational control and 广泛控制氨基酸合成1样蛋白1抗体performs an EF3-related function on the ribosome by regulating GCN2 protein kinase (EIF2AK1-4) activity. Subunit: Interacts with IMPACT; prevents the interaction with GCN2 protein kinase (EIF2AK1-4) (By similarity). Subcellular Location: Cytoplasmic Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the GCN1 family. Contains 24 HEAT repeats. Database links: UniProtKB/Swiss-Prot: Q92616.6 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
广泛控制氨基酸合成1样蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid