骋蛋白结合蛋白1抗体
规格：1尘驳/1尘濒
英文名： GBP1
别名： GBP 1; GBP-1; GBP1; GBP1_HUMAN; GTP binding protein 1; GTP-binding protein 1; Guanine nucleotide binding protein 1; Guanine nucleotide-binding protein 1; Guanylate binding protein 1; Guanylate binding
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GBP1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
骋蛋白结合蛋白1抗体产物介绍：background: Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in 骋蛋白结合蛋白1抗体cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS. Function: Binds GTP, GDP and GMP. Subunit: Homodimerizes upon GTP-binding, dimerization is required for the second hydrolysis step from GDP to GMP. Can also heterodimerize with other members of the family. Subcellular Location: Cytoplasm. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization 骋蛋白结合蛋白1抗体requires isoprenylation and the presence of another IFN-gamma-induced factor. Similarity: Belongs to the GBP family. Database links: Entrez Gene: 26284 Human Entrez Gene: 57837 Mouse Entrez Gene: 363646 Rat Omim: 607435 Human SwissProt: O75616 Human SwissProt: Q9CZU4 Mouse SwissProt: Q5EBA0 Rat Unigene: 3426 Human Unigene: 21096 Mouse Unigene: 99076 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白结合蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid