β葡萄糖苷酶2抗体
规格：1尘驳/1尘濒
英文名： GBA2
别名： AD035; Beta glucocerebrosidase 2; Beta glucosidase 2; DKFZp762K054; glucosidase, beta (bile acid) 2; Glucosylceramidase 2; KIAA1605; MGC16895; Non lysosomal glucosylceramidase; GBA2_HUMAN.
分子量： 105kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GBA2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：细胞膜
β葡萄糖苷酶2抗体产物介绍：background: Beta-glucosidase 2, also known as non-lysosomal glucosylceramidase (NLGase), Glucosylceramidase 2, GBA2 or AD035, is a 927 amino acid non-lysosomal glucosylceramidase that catalyzes glucosylceramide into ceramide and free glucose, and is suggested to play a role in carbohydrate transport and metabolism. A single-pass membrane protein, Beta-glucosidase 2 exists as three alternatively spliced isoforms that are widely expressed but found at highest levels in placenta, kidney, brain, skeletal muscle, kidney and heart, with low levels found in liver. Beta-glucosidase 2 activity has been linked to sphingomyelin generation and prevention of glycolipid accumulationβ葡萄糖苷酶2抗体. The gene encoding Beta-glucosidase 2 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Function: GBA2 is a non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. It is involved in sphingomyelin generation and prevention of glycolipid accumulation. GBA2 may also catalyze the hydrolysis of bile acidβ葡萄糖苷酶2抗体 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Subcellular Location: Cell membrane; Single-pass membrane protein. Note=Not localized to lipid rafts. Tissue Specificity: Widely expressed. Highly expressed in brain, heart, skeletal muscle, kidney and placenta and expressed at lower level in liver. Similarity: Belongs to the non-lysosomal glucosylceramidase family. Database links: UniProtKB/Swiss-Prot: Q9HCG7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β葡萄糖苷酶2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 发育生物学 信号转导 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid