生长因子受体结合适应蛋白抗体
规格：1尘驳/1尘濒
英文名： GAPT
别名： C5orf29; Gapt; GAPT_HUMAN; Grb2-binding adaptor transmembrane; Growth factor receptor-bound protein 2-binding adapter protein; Growth factor receptor-bound protein 2-binding adapter protein, transmemb
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GAPT
交叉反应：贬耻尘补苍,
细胞定位：细胞膜
生长因子受体结合适应蛋白抗体产物介绍：background: With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q 生长因子受体结合适应蛋白抗体or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The C5orf29 gene product has been provisionally designated C5orf29 pending further characterization. Function: Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells. Subunit:生长因子受体结合适应蛋白抗体 Interacts with GRB2. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells. Similarity: Belongs to the GAPT family. Database links: UniProtKB/Swiss-Prot: Q8N292.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长因子受体结合适应蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid