γ-微管蛋白复合物骋颁笔3抗体
规格：1尘驳/1尘濒
英文名： GCP3
别名： Gamma tubulin complex component 3; Gamma-ring complex protein 104 kDa; Gamma-tubulin complex component 3; GCP-3; GCP3; GCP3_HUMAN; h104p; hGCP3; hGrip104; hSpc98; SPBC98; Spc98p; Spindle pole body pro
分子量： 104kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GCP3/Gam
交叉反应：Human, Mouse, Rat, Chicken, Cow, Sheep, Xenopus laevis
细胞定位：细胞浆
γ-微管蛋白复合物骋颁笔3抗体产物介绍：background: The Gamma-Tubulin complex is composed of Gamma Tubulin and the Gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. Gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the Gamma-Tubulin complex. GCP3 (Gamma-Tubulin complex component 3), γ-微管蛋白复合物骋颁笔3抗体also known as TUBGCP3 or SPBC98, localizes to the centrosome and is a ubiquitously expressed 907 amino acid member of the Gamma-Tubulin complex. Like GCP2 and Gamma Tubulin, GCP3 is conserved in all eukaryotes, suggesting that it is part of a core unit involved in eukaryotic microtubule nucleation. Three isoforms of GCP3 exist due to alternative splicing events. Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Subunit: Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4,γ-微管蛋白复合物骋颁笔3抗体 TUBGCP5 and TUBGCP6. Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBGCP3 and CDK5RAP2. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the GCP family. Database links: Entrez Gene: 10426 Human Entrez Gene: 259279 Mouse SwissProt: Q96CW5 Human SwissProt: P58854 Mouse Unigene: 224152 Huma Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ-微管蛋白复合物骋颁笔3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid