多肽狈-乙酰氨基半乳糖转移酶10抗体
规格：1尘驳/1尘濒
英文名： GALNT10
别名： DKFZp586H0623; FLJ00205; FLJ11715; GalNAc T10; GalNAc transferase 10; GalNAc-T10; GalNAcT10; GALNT10; GLT10_HUMAN; Polypeptide GalNAc transferase 10; Polypeptide N-acetylgalactosaminyltransferase 10;
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNT10/
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
多肽狈-乙酰氨基半乳糖转移酶10抗体产物介绍：background: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues of various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T10 (Polypeptide N-acetylgalactosaminyltransferase 10), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, is a 603 amino acid single-pass type II membrane protein that prefers Muc5Ac and EA2 peptide substrates. The N-terminal domain is involved in 多肽狈-乙酰氨基半乳糖转移酶10抗体substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T10 is widely expressed, with highest levels found in small intestine. There are four isoforms of GalNAc-T10 that are produced as a result of alternative splicing events. Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Subcellular多肽狈-乙酰氨基半乳糖转移酶10抗体 Location: Golgi apparatus membrane. Tissue Specificity: Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Database links: Entrez Gene: 55568 Human Entrez Gene: 171212 Mouse Entrez Gene: 170501 Rat Omim: 608043 Human SwissProt: Q86SR1 Human SwissProt: Q6P9S7 Mouse SwissProt: Q925R7 Rat Unigene: 726056 Human Unigene: 271670 Mouse Unigene: 60224 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多肽狈-乙酰氨基半乳糖转移酶10抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid