G蛋白偶联受体结合蛋白α11/Gα 11 抗体
规格：1尘驳/1尘濒
英文名： GNA11
别名： G alpha-11; G-protein subunit alpha-11; GNA11; GNA11_HUMAN; Guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GNA11
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
G蛋白偶联受体结合蛋白α11/Gα 11 抗体产物介绍：background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Ga subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4).G蛋白偶联受体结合蛋白α11/Gα 11 抗体 The Gq class includes G alpha 15, G alpha 14, G alpha 11 and G alpha q, two of which, G alpha 11 and G alphaq, are abundant in brain and lung and present at lower levels in a variety of tissues (6). Function: Guanine nucleotide-binding proteinsG蛋白偶联受体结合蛋白α11/Gα 11 抗体 (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C. Subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Subcellular Location: Cell membrane. Similarity: Belongs to the G-alpha family. G(q) subfamily. Database links: UniProtKB/Swiss-Prot: P29992.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体结合蛋白α11/Gα 11 抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 结合蛋白 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid