岩藻糖基转移酶6抗体
规格：1尘驳/1尘濒
英文名： FUT6
别名： Alpha (1,3) fucosyltransferase; EC=2.4.1.65; FCT3A; Fuc TVI; Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase; FUT6_HUMAN.
分子量： 42kDa
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FUT6/Fuc
交叉反应：贬耻尘补苍,
细胞定位：细胞浆 细胞膜
岩藻糖基转移酶6抗体产物介绍：background: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles岩藻糖基转移酶6抗体, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Function: Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP-beta-fucose to alpha-2,3 sialylated substrates. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note: Membrane-bound form in trans cisternae岩藻糖基转移酶6抗体 of Golgi. Tissue Specificity: Kidney, liver, colon, small intestine, bladder, uterus and salivary gland. Similarity: Belongs to the glycosyltransferase 10 family. Database links: Entrez Gene: 2528 Human Omim: 136836 Human SwissProt: P51993 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
岩藻糖基转移酶6抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid