叉头蛋白狈2抗体
规格:1尘驳/1尘濒
英文名: FOXN2
别名: 3230402J05Rik; 6030465J18Rik; Fkh19; Forkhead box N2; Forkhead box protein N2; Foxn1; foxn2; FOXN2_HUMAN; HTLF; Human T-cell leukemia virus enhancer factor.
分子量: 47kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FOXN2
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:细胞核
叉头蛋白狈2抗体产物介绍:background: The forkhead domain-containing gene family (Fox) comprises over 20 members in mammals and is defined by a conserved 110 amino-acid motif containing a winged helix structure DNA-binding domain. The members of this gene family have been implicated as key regulators of embryogenesis, cell cycling, cell lineage restriction and cancer. As such, FOXN2 contains a domain with homology to the forkhead DNA binding domain. FOXN2, or Human T-cell leukemia virus enhancer factor, is a 341 amino acid protein mapping 叉头蛋白狈2抗体to human gene FOXN2, which has been localized to human chromosome 2p16-p22. This protein, encoded by a 1239-bp cDNA isolated from the Jurkat cDNA library, is capable of binding to a region of the human T-cell leukemia virus long terminal repeat (HTLV-I LTR) located between amino acids 155 and 117. This purine-rich region is important in the regulation of gene expression by the Ets family of transcription factors. 叉头蛋白狈2抗体FOXN2 is a unique cellular gene that may function in the transcriptional regulation of HTLV-I LTR. Function: Binds to the purine-rich region in HTLV-I LTR. Subcellular Location: Nucleus. Similarity: Contains 1 fork-head DNA-binding domain. Database links: UniProtKB/Swiss-Prot: P32314.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
叉头蛋白狈2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞周期蛋白 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid