胞吐囊复合体蛋白2抗体
规格:1尘驳/1尘濒
英文名: EXOC2
别名: exocyst complex component 2; exocyst complex component Sec5; FLJ11026; SEC5; SEC5 like 1; SEC5L1; Sec5p; EXOC2_HUMAN.
分子量: 104kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human EXOC2/SE
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
细胞定位:细胞浆 细胞膜
胞吐囊复合体蛋白2抗体产物介绍:background: The mammalian exocyst complex (sec 6/8) is a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Sec 5 is one of eight exocyst complex subunits: Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. Exocyst complex regulation depends upon Sec5 binding Ral in a GTP-dependent manner. Human Sec5 maps to chromosome 6p25.3. Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8.胞吐囊复合体蛋白2抗体 Interacts with EXOC3L1 (By similarity). Interacts with RALA and GNEFR/DELGEF. Interaction with GNEFR occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALB. Subcellular Location: Plasma membrane. Tissue Specificity: Widely expressed with highest levels in brain and placenta. Similarity: Belongs to the SEC5 family. Contains 1 IPT/TIG domain. Database胞吐囊复合体蛋白2抗体 links: Entrez Gene: 55770 Human Entrez Gene: 66482 Mouse Entrez Gene: 171455 Rat SwissProt: Q96KP1 Human SwissProt: Q9D4H1 Mouse SwissProt: O54921 Rat Unigene: 484412 Human Unigene: 293510 Mouse Unigene: 2869 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞吐囊复合体蛋白2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid