结核分枝杆菌分泌性蛋白贰厂础罢6抗体
规格:1尘驳/1尘濒
英文名: ESAT6
别名: 6 kDa early secretory antigenic target; 6 kDa early secretory antigenic target ESXA; ESAT 6; esaT6; ESXA; ESXA_MYCTU; ESAT-6.
分子量: 10kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Mycobacterium
交叉反应:Mycobacterium tuberculosis, Mycobacterium szulgai, Mycobacte
细胞定位:分泌型蛋白
结核分枝杆菌分泌性蛋白贰厂础罢6抗体产物介绍:background: Mycobacterium tuberculosis is a slow-growing obligate aerobic bacillus that causes most cases of tuberculosis (TB). It is a small, rod-like microbe that can withstand weak disinfectants and survive in a dry state for weeks, but can only grow within a host organism. M. tuberculosis has a thick waxy cell wall that is responsible for the typical caseous granuloma formation in tuberculosis. ESAT6 is a protein secreted by M. tuberculosis that induces a strong immune response in infected organisms, making it a strong结核分枝杆菌分泌性蛋白贰厂础罢6抗体 candidate for the development of a vaccine against tuberculosis. ESAT6 may also be useful in the detection of the disease. Deletion of the ESAT6 gene leads to the loss of virulence of M. tuberculosis. Function: The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models结核分枝杆菌分泌性蛋白贰厂础罢6抗体. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response. Subcellular Location: Secreted Similarity: Belongs to the ESAT-6 (esx) family. Gene ID: 886209 Database links: Entrez Gene: 886209 MYCTU SwissProt: P9WNK6 MYCTU Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
结核分枝杆菌分泌性蛋白贰厂础罢6抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid