细胞表面趋化因子受体7抗体
规格：1尘驳/1尘濒
英文名： CCR7
别名： BLR 2; BLR2; C C chemokine receptor type 7; C C CKR 7; CC chemokine receptor 7; CC chemokine receptor type 7; CC CKR 7; CCCKR7; CCR 7; CD 197; CD197; CD197 antigen; CDW197; Chemokine C C motif recepto
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCR7
交叉反应：Human, Mouse, Rat, Dog,
细胞定位：细胞膜
细胞表面趋化因子受体7抗体产物介绍：background: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008] Function: Receptor for the MIP-3-beta chemokine. Probable 细胞表面趋化因子受体7抗体mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene 细胞表面趋化因子受体7抗体ID: 1236 Database links: Entrez Gene: 1236 Human Entrez Gene: 12775 Mouse Entrez Gene: 287673 Rat Omim: 600242 Human SwissProt: P32248 Human SwissProt: P47774 Mouse Unigene: 370036 Human Unigene: 2932 Mouse Unigene: 229736 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 趋化因子是当今细胞因子研究领域的热点之一,它参与多种**及炎症反应,在感染、肿瘤的生长与转移、组织修复及创伤**等病理生理过程中发挥重要作用.CCR7在肿瘤的生长与转移方面起到一定的作用.
细胞表面趋化因子受体7抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid