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Ó¢ÎÄÃû£º ECHDC2

±ðÃû£º 1300017C12Rik; 2610009M20Rik; D4Ertd765e; Enoyl Coenzyme A hydratase domain containing 2; FLJ10948; Enoyl-CoA hydratase domain-containing protein 2; RGD1308525; RP23-379K6.3; ECHD2_HUMAN.

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´¢´æÒº£º0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

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´¿»¯·½·¨£ºaffinity purified by Protein A

**Ô­£ºKLH conjugated synthetic peptide derived from human ECHDC2

½»²æ·´Ó¦£ºHuman, Mouse, Rat, Pig, Cow, Horse, Zebrafish, Sheep,

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Ï©õ£¸¨Ã¸´¡Ë®ºÏøº¬½á¹¹Óòµ°°×2¿¹Ìå²úÎï½éÉÜ£ºbackground: ECHDC2 is a 292 amino acid mitochondrial protein that exists as two isoforms which are produced by alternative splicing events. The gene encoding ECHDC2 maps to chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 encodes a large number of disease-associated proteins, including Lamin A which, when expressed abnormally, can build up in the nucleus and cause nuclear blebs, a characteristic of theÏ©õ£¸¨Ã¸´¡Ë®ºÏøº¬½á¹¹Óòµ°°×2¿¹Ìå rare aging disease Hutchinson-Gilford progeria. Additionally, genes that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons Disease, Gaucher disease, schizophrenia and Usher syndrome are all located on chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function:Ï©õ£¸¨Ã¸´¡Ë®ºÏøº¬½á¹¹Óòµ°°×2¿¹Ìå ECHDC2 belongs to the enoyl-CoA hydratase/isomerase family. There are two named isforms. Subcellular Location: Mitochondrion (Potential). Similarity: Belongs to the enoyl-CoA hydratase/isomerase family. Database links: UniProtKB/Swiss-Prot: Q86YB7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Ï©õ£¸¨Ã¸´¡Ë®ºÏøº¬½á¹¹Óòµ°°×2¿¹Ìå²úÎïÓ¦ÓãºWB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 £¨Ê¯À¯ÇÐÆ¬Ðè×ö¿¹Ô­ÐÞ¸´£© not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

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´¢´æÌõ¼þ£º Store at -20 ¡ãC for one year. Avoid repeated freeze/thaw cycles.

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Íâ¹Û£º Lyophilized or Liquid


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