顿狈础酶1样蛋白1抗体
规格:1尘驳/1尘濒
英文名: DNASE1L1
别名: Deoxyribonuclease I-like 1; Deoxyribonuclease I like 1; Deoxyribonuclease-1-like 1; DNAS1L1; DNase I like 1; DNase I like muscle specific; DNase I lysosomal like; DNase I-like 1; DNase X; DNASE1L1; DN
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DNASE1L1
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞浆
顿狈础酶1样蛋白1抗体产物介绍:background: DNASE1L1 is a 302 amino acid protein that localizes to the endoplasmic reticulum and belongs to the deoxyribonuclease family. Expressed at high levels in cardiac and skeletal muscle and at lower levels in a variety of tissues throughout the body, DNASE1L1 exists as multiple alternatively spliced isoforms and is thought to function in a similar manner to DNase l, possibly mediating internucleosomal DNA degradation via catalytic cleavage events. The gene encoding DNASE1L1 maps to human chromosome顿狈础酶1样蛋白1抗体 X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Subcellular Location: Endoplasmic 顿狈础酶1样蛋白1抗体reticulum. Tissue Specificity: Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain. Similarity: Belongs to the DNase I family. Database links: UniProtKB/Swiss-Prot: P49184.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿狈础酶1样蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号 神经生物学 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid