富含半胱氨酸蛋白结合蛋白抗体
规格：1尘驳/1尘濒
英文名： CSRP2BP
别名： ADA2A containing complex subunit 2; ADA2A-containing complex subunit 2; ATAC2; CRP2 binding partner; CRP2-binding partner; CRP2BP; CSR2B_HUMAN; CSRP2 binding protein; CSRP2-binding protein; Csrp2bp; C
分子量： 89kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CSRP2BP
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
富含半胱氨酸蛋白结合蛋白抗体产物介绍：background: CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously富含半胱氨酸蛋白结合蛋白抗体 expressed nuclear protein, with highest expression in skeletal muscle and heart. Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. Subunit: Interacts with the LIM 1 domain of CSRP2. Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A,富含半胱氨酸蛋白结合蛋白抗体 MBIP and WDR5. Subcellular Location: Nucleus. Cytoplasm. Mainly nuclear. Tissue Specificity: Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung. Similarity: Contains 1 N-acetyltransferase domain. Database links: Entrez Gene: 57325 Human Entrez Gene: 228714 Mouse SwissProt: Q9H8E8 Human SwissProt: Q8CID0 Mouse Unigene: 488051 Human Unigene: 728790 Human Unigene: 227925 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含半胱氨酸蛋白结合蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid