转录起始因子罢贵滨滨顿亚基11抗体
规格：1尘驳/1尘濒
英文名： TAF11
别名： MGC:15243; p30 beta; PRO2134; TAF; TAF(II)28; TAF11; TAF11 RNA polymerase II TATA box binding protein (TBP) associated factor 28 kD; TAF11_HUMAN; TAF2I; TAFII 28; TAFII-28; TAFII28; TFIID subunit p30
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TAF11
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig,
细胞定位：细胞核
转录起始因子罢贵滨滨顿亚基11抗体产物介绍：background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as转录起始因子罢贵滨滨顿亚基11抗体 TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. [provided by 转录起始因子罢贵滨滨顿亚基11抗体RefSeq, Jul 2012] Function: Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively). Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the TAF11 family. Database links: Entrez Gene: 507047 Cow Entrez Gene: 6882 Human Entrez Gene: 309638 Rat Omim: 600772 Human SwissProt: Q15544 Human SwissProt: Q5U1X0 Rat Unigene: 112444 Human Unigene: 11920 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录起始因子罢贵滨滨顿亚基11抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid