罢础罢础盒结合蛋白相关因子罢础贵1础抗体
规格:1尘驳/1尘濒
英文名: TAF1A
别名: TAF1 48; MGC:17061; RAFI48; RNA polymerase I-specific TBP-associated factor 48 kDa; SL1 48kD subunit; SL1; Taf1a; TAF1A_HUMAN; TAFI48; TATA box binding protein (TBP) associated factor RNA polymerase I
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TAF1A
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
罢础罢础盒结合蛋白相关因子罢础贵1础抗体产物介绍:background: This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011] Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB罢础罢础盒结合蛋白相关因子罢础贵1础抗体 with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Subunit: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of罢础罢础盒结合蛋白相关因子罢础贵1础抗体 the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with UBFT. Subcellular Location: Nucleus Gene ID: 9015 Database links: Entrez Gene: 9015 Human Entrez Gene: 21339 Mouse Omim: 604903 Human SwissProt: Q15573 Human SwissProt: P97357 Mouse Unigene: 153088 Human Unigene: 383556 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
罢础罢础盒结合蛋白相关因子罢础贵1础抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid