莱姆病螺旋体抗体
规格:1尘驳/1尘濒
英文名: Borrelia burgdorferi
别名: B burgdorferi; B. burgdorferi; B.burgdorferi; Lyme disease.
分子量: 83kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Borrelia burgd
交叉反应:Reacts with Treponema pallidum, B. hermsii and B. parkerii.
细胞定位:
莱姆病螺旋体抗体产物介绍:background: Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 莱姆病又称;游走性红斑(EM)、慢性游走性红斑(ECM)、莱姆病螺旋体抗体慢性萎缩性肌皮炎(ACA)、慢性脑脊髓炎、良性**细胞增生症、慢性游走性红斑性关节炎、少年类风湿性关节炎、莱姆关节炎等。 莱姆病(Lyme disease)是由伯氏疏螺旋体(Bolrelia burgdorferi)引起的一种慢性自然疫源性**,因在1977年*先发现于美国康涅狄克州的莱姆镇(Lyme townl而得名。 临床表现初期多有典型皮肤损害——慢性游走性红斑(ECM),同时伴有**、发热、寒战、疲乏不适.局部**结肿大等症状,莱姆病螺旋体抗体后期表现为神经系统、循环系统、运动系统等呈间歇性、交替性出现的各种损害。具有分布广、病程长、病死率较高等特点。如能早期诊断、早期**常可痊愈。否则会出现严重并发症。该病多发于气候温和的夏季,患者多在林木茂密地区野外活动时被蜱叮咬而感染,因而,几种嗜血硬蜱是主要传播媒介,一些脊椎动物如鼠、鹿、狗、兔等是其主要宿主。 某些脊椎动物被认为是莱姆病的重要传染源。不同地区传染源的种类有所不同。在北美,白足鼠和白尾鹿被认为是重要传染源,一些宠物和牲畜如狗、马、羊、牛等因与人类生活紧密相连,也引起广泛关注。在欧洲,白尾鹿被认为是重要传染源,狗也与一些地区该病的流行有关。我国已从黑线姬鼠、白腹鼠、社鼠、小家鼠、嗣婧、野兔及病人体内分离出病原体,一些家畜的感染率也很高,但作为传染源的意义如何尚需进一步调查。目前已分离出伯氏疏螺旋体或检出特异性抗体的动物有自足鼠、金花鼠、负鼠、田鼠、褐家鼠、小家鼠、天山蹶鼠、小林姬鼠、白尾鹿、黑尾鹿、浣熊、狗、牛、马、羊、兔、狼、狐狸、燕子、喜鹊等。
莱姆病螺旋体抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid