粘蛋白/岩藻糖基转移酶3抗体
规格:1尘驳/1尘濒
英文名: Blood Group Lewis b
别名: Blood group Lewis alpha-4-fucosyltransferase; Fucosyltransferase 3; Fucosyltransferase III; FucT-III; FUT3; FUT3_HUMAN; Galactoside 3(4)-L-fucosyltransferase; gastric mucin; leB; lewis antigen system;
分子量: 42kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Blood Gr
交叉反应:贬耻尘补苍,
细胞定位:细胞浆 细胞膜
粘蛋白/岩藻糖基转移酶3抗体产物介绍:background: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, 粘蛋白/岩藻糖基转移酶3抗体which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Blood Group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins. Function: Blood group Lewis b is a carbohydrate determinant carried on 粘蛋白/岩藻糖基转移酶3抗体both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Subcellular Location: Plasma membrane - adsorbed onto the surface of erythrocytes. Tissue Specificity: Highly expressed in stomach, colon, smallintestine, lung and kidney and to a lesser extent in salivarygland, bladder, uterus and liver. Similarity: Belongs to the glycosyltransferase 10 family. Gene ID: 2525 Database links: Entrez Gene: 2525 Human Omim: 111100 Human SwissProt: P21217 Human Unigene: 169238 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
粘蛋白/岩藻糖基转移酶3抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞粘附分子 糖蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid