蛋白翱岩藻糖基转移酶2抗体
规格:1尘驳/1尘濒
英文名: POFUT2
别名: C21orf80; EC 2.4.1.221; FUT 13; FUT13; GDP fucose protein O fucosyltransferase 2; GDP-fucose protein O-fucosyltransferase 2; KIAA0958; O FucT 2; O-FucT-2; OFucT2; OFUT2_HUMAN; Peptide O fucosyltransfe
分子量: 25, 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human POFUT2
交叉反应:Human, Mouse, Rat, Chicken, Rabbit, Guinea Pig,
细胞定位:
蛋白翱岩藻糖基转移酶2抗体产物介绍:background: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008] Function: Catalyzes the reaction that attaches蛋白翱岩藻糖基转移酶2抗体 fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Subcellular Location: Endoplasmic reticulum. Tissue Specificity: Isoform A is expressed in fetal liver and peripheral blood lymphocytes. Isoform B is expressed in spleen, lung, testis, bone marrow, thymus, pancreas, prostate, fetal brain, fetal liver and fetal kidney. Isoform C is expressed in brain, heart, spleen, liver, lung, stomach, testis, placenta, skin, thymus, pancreas, mammary gland, prostate, fetal brain, fetal liver and fetal heart.蛋白翱岩藻糖基转移酶2抗体 Similarity: Belongs to the glycosyltransferase 68 family. Database links: Entrez Gene: 31098 Fruit fly (Drosophila melanogaster) Entrez Gene: 23275 Human Entrez Gene: 80294 Mouse Entrez Gene: 309686 Rat Omim: 610249 Human SwissProt: Q9W589 Fruit fly (Drosophila melanogaster) SwissProt: Q9Y2G5 Human SwissProt: Q8VHI3 Mouse Unigene: 4643 Fruit fly (Drosophila melanogaster) Unigene: 592164 Human Unigene: 203556 Mouse Unigene: 11702 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白翱岩藻糖基转移酶2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid