富含脯氨酸核受体共激活因子2抗体
规格:1尘驳/1尘濒
英文名: PNRC2
别名: 0610011E17Rik; D4Bwg0593e; FLJ20312; MGC11707; MGC93828; MGC99541; OTTMUSP00000010360; OTTMUSP00000010366; pnrc2; PNRC2_HUMAN; Proline rich nuclear receptor coactivator 2; Proline-rich nuclear recepto
分子量: 16kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PNRC2
交叉反应:Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位:细胞核 细胞浆
富含脯氨酸核受体共激活因子2抗体产物介绍:Function: Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure. Subcellular Location: Nucleus. Cytoplasm > P-body.富含脯氨酸核受体共激活因子2抗体 Tissue Specificity: Expressed in heart, lung, muscle and brain. Similarity: Belongs to the PNRC family. PNRC2 subfamily. Database links: Entrez Gene: 767836 Cow Entrez Gene: 100505603 Human Entrez Gene: 55629 Human Entrez Gene: 52830 Mouse Entrez Gene: 100125373 Rat Entrez Gene: 565522 Zebrafish Omim: 611882 Human SwissProt: Q0VCW6 Cow SwissProt: Q9NPJ4 Human SwissProt富含脯氨酸核受体共激活因子2抗体: Q9CR73 Mouse SwissProt: Q66HE1 Rat SwissProt: B7TWP7 Zebrafish Unigene: 512636 Human Unigene: 644217 Human Unigene: 716935 Human Unigene: 7862 Human Unigene: 29159 Mouse Unigene: 118788 Rat Unigene: 70123 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含脯氨酸核受体共激活因子2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid