磷脂特异性磷脂酶础1抗体
规格:1尘驳/1尘濒
英文名: PLA1A
别名: AA986889; NMD; OTTHUMP00000215248; OTTHUMP00000215249; OTTHUMP00000215250; Phosphatidylserine specific phospholipase A1; Phosphatidylserine specific phospholipase A1alpha; Phosphatidylserine-specific
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PLA1A
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
磷脂特异性磷脂酶础1抗体产物介绍:background: The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011] Function: Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the磷脂特异性磷脂酶础1抗体 form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production. Subcellular Location: Secreted. Tissue Specificity: Widely expressed磷脂特异性磷脂酶础1抗体. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney. Similarity: Belongs to the AB hydrolase superfamily. Lipase family. Database links: Entrez Gene: 51365 Human Entrez Gene: 85311 Rat Omim: 607460 Human SwissProt: Q53H76 Human SwissProt: P97535 Rat Unigene: 437451 Human Unigene: 10696 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷脂特异性磷脂酶础1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid