跨膜内耳蛋白罢惭滨贰抗体
规格：1尘驳/1尘濒
英文名： TMIE
别名： deafness autosomal recessive 6; DFNB6; transmembrane inner ear; transmembrane inner ear expressed protein; transmembrane inner ear protein.
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TMIE
交叉反应：Human, Mouse,
细胞定位：细胞膜
跨膜内耳蛋白罢惭滨贰抗体产物介绍：background: This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq, Mar 2009] Function: Unknown. The protein may play some role in a cellular membrane location. May reside within an internal membrane compartment and 跨膜内耳蛋白罢惭滨贰抗体function in pathways such as those involved in protein and/or vesicle trafficking. Alternatively, the mature protein may be localized in the plasma membrane and serve as a site of interaction for other molecules through its highly charged C-terminal domain. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: The disease is caused by mutations affecting the gene represented in this entry. 跨膜内耳蛋白罢惭滨贰抗体Disease description:A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Database links: Entrez Gene: 259236 Human Entrez Gene: 20776 Mouse SwissProt: Q8NEW7 Human SwissProt: Q8K467 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
跨膜内耳蛋白罢惭滨贰抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 跨膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid