跨膜前列腺雄**诱导蛋白1抗体
规格：1尘驳/1尘濒
英文名： TMEPAI
别名： PMEPA_HUMAN; PMEPA1; Prostate transmembrane protein, androgen induced 1; Solid tumor associated 1 protein; Solid tumor-associated 1 protein; STAG1; TMEPAI; Transmembrane prostate androgen induced prot
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TMEPAI
交叉反应：Human, Mouse,
细胞定位：细胞膜
跨膜前列腺雄**诱导蛋白1抗体产物介绍：background: This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for 跨膜前列腺雄**诱导蛋白1抗体this gene. [provided by RefSeq, Dec 2011] Function: Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4. Subcellular Location: Cell membrane. Tissue Specificity: Highest expression in prostate. Also expressed in ovary. Similarity: Belongs to the PMEPA1 family. Database links: Entrez Gene: 56937 跨膜前列腺雄**诱导蛋白1抗体Human Omim: 606564 Human SwissProt: Q969W9 Human Unigene: 517155 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
跨膜前列腺雄**诱导蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 生长因子和** 跨膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid