平滑肌样蛋白1抗
规格：1尘驳/1尘濒
英文名： SMTNL1
别名： Calponin homology associated smooth muscle protein; CHASM; OTTHUMP00000235021; Smoothelin like 1; Smoothelin like protein 1; SMTNL1.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SMTNL1
交叉反应：Human, Mouse,
细胞定位：细胞浆
平滑肌样蛋白1抗产物介绍：background: SMTNL1, which is a member of the smoothelin (SMTN; MIM 602127) family, regulates contraction and relaxation of skeletal and smooth muscle fibers and mediates vascular adaptation to exercise (Wooldridge et al., 2008 [PubMed 18310078]).[supplied by OMIM, Dec 2010] Function: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). Subcellular Location: Cytoplasm ?myofibril. Cytoplasm ?myofibril ?sarcomere ?I band By similarity. Cytoplasm ?myofibril ?sarcomere ?M line平滑肌样蛋白1抗. Nucleus. Note: Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm. Phosphorylation at Ser-301 promotes translocation to the nucleus, Tissue Specificity: Expressed in striated muscles, specifically in type 2a fibers (at protein level). Post-translational modifications: Maximal phosphorylation of Ser-299 correlates with maximal relaxation of aorta in response to acetylcholine. Similarity: Belongs to 平滑肌样蛋白1抗the smoothelin family. Contains 1 CH (calponin-homology) domain. Database links: Entrez Gene: 219537 Human Omim: 613664 Human SwissProt: A8MU46 Human Unigene: 68756 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
平滑肌样蛋白1抗产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 细胞骨架 表观遗传学
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid