厂惭狈相关蛋白抗体
规格:1尘驳/1尘濒
英文名: SMNDC1
别名: 30 kDa splicing factor SMNrp; MGC106917; MGC112663; SMN related protein; SMN-related protein; smndc1; SMNR; SPF30; SPF30_HUMAN; Splicing factor 30, survival of motor neuron-related; Survival motor neu
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SMNDC1
交叉反应:Human, Mouse, Rat, Chicken, Cow, Rabbit, Zebrafish, Guinea Pig,
细胞定位:细胞核
厂惭狈相关蛋白抗体产物介绍:background: This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008] Function: Necessary for spliceosome assembly. 厂惭狈相关蛋白抗体Overexpression causes apoptosis. Subcellular Location: Nucleus speckle. Nucleus > Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. Tissue Specificity: Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas. Similarity: Belongs to the SMN family. Contains 1 Tudor domain. Database links: Entrez Gene: 520500 Cow Entrez Gene: 10285 Human Entrez Gene: 76479 Mouse Entrez Gene: 287768 Rat Entrez Gene: 572679 Zebrafish Omim: 603519 Human SwissProt: Q3T045 Cow SwissProt: O75940 Human 厂惭狈相关蛋白抗体SwissProt: Q8BGT7 Mouse SwissProt: Q4QQU6 Rat SwissProt: Q7ZV80 Zebrafish Unigene: 632093 Human Unigene: 313687 Mouse Unigene: 103854 Rat Unigene: 75917 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
厂惭狈相关蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid