希佩尔-林道结合蛋白抗体
规格:1尘驳/1尘濒
英文名: PFDN3
别名: HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1;
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PFDN3
交叉反应:Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位:细胞核 细胞浆
希佩尔-林道结合蛋白抗体产物介绍:background: The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015] Function: Binds specifically to cytosolic希佩尔-林道结合蛋白抗体 chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Subcellular Location: Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus. Tissue Specificity: Ubiquitous. Similarity: Belongs to the prefoldin subunit alpha family. Database links: Entrez 希佩尔-林道结合蛋白抗体Gene: 508727 Cow Entrez Gene: 481089 Dog Entrez Gene: 7411 Human Entrez Gene: 22327 Mouse Omim: 300133 Human SwissProt: Q2TBX2 Cow SwissProt: P61758 Human SwissProt: P61759 Mouse Unigene: 436803 Human Unigene: 8294 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
希佩尔-林道结合蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转录调节因子 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid